- Combination birth control pills (containing estrogen + progestin ) have a known, small increased risk of venous thromboembolism (VTE)
- Higher risk with pills containing drospirenone, desogestrel, or gestodene vs. levonorgestrel
- Risk is still low — about 3–9 per 10,000 users per year (vs. 2 in non-users)
✅ What to do: Discuss your personal risk (age, smoking, family history) with your doctor. Safer options exist.
2. Hormone Replacement Therapy (HRT)
- Oral HRT for menopause has been linked to a higher risk of blood clots
- Transdermal patches or gels may carry lower risk
✅ What to do: Use the lowest effective dose for the shortest time . Talk to your doctor about alternatives.
3. Some Antipsychotics & Antidepressants
- Certain atypical antipsychotics (e.g., clozapine, olanzapine) may increase clotting risk due to sedation, weight gain, and immobility
- Rare cases of myocarditis or thrombosis reported
✅ What to do: Never stop medication without medical advice. Monitor for symptoms.
4. Janssen (Johnson & Johnson) COVID-19 Vaccine (Rare)
- In 2021, the FDA and CDC identified a very rare risk of thrombosis with thrombocytopenia syndrome (TTS) — about 3 cases per 1 million doses
- Mostly in women under 50
- The vaccine remains available with a boxed warning
✅ Note: This risk is extremely rare and far outweighed by the benefits for most people.
What Are the Warning Signs of a Blood Clot?
If you’re on any medication with clotting risks, know the symptoms:
- 🦵 Swelling, pain, redness in one leg (deep vein thrombosis)
- 🫁 Sudden shortness of breath, chest pain, coughing up blood (pulmonary embolism)
- ❤️ Chest pressure, arm pain, nausea (heart attack)
- 🧠 Sudden weakness, slurred speech, vision changes (stroke)
🚨 Seek emergency care immediately if you experience any of these.
What Should You Do?
✅ Don’t stop your medication without talking to your doctor
✅ Review your meds with your healthcare provider — especially if you have risk factors (smoking, obesity, clotting history)
✅ Know the symptoms of blood clots and heart issues
✅ Stay informed through trusted sources:
Final Thoughts
Yes, some medications carry a risk of blood clots — but so does surgery, pregnancy, and prolonged immobility .
The key is informed decision-making , not fear.
Health authorities issue warnings not to scare you — but to protect you .
So if you’re concerned about a medication you’re taking:
Talk to your doctor. Ask questions. Get clarity.
Because your health deserves facts, not fear .