As we age, many of us become more aware of changes in memory and thinking. While some cognitive changes are a normal part of aging, certain medications — especially when used long-term — have been associated with an increased risk of cognitive decline or dementia-like symptoms .
The key word? Associated .
That doesn’t mean these drugs cause dementia — but research suggests they may contribute to confusion, memory issues, or reduced mental clarity in some people, especially older adults.
Let’s explore 8 types of medications that have been studied for their potential impact on brain health — and what you can do to protect your mind while managing your health .
🔍 The Science: Anticholinergic Drugs & Brain Health
The most well-researched link between medications and cognitive decline involves anticholinergic drugs — medicines that block acetylcholine , a brain chemical vital for memory and learning.
A landmark 2019 study in JAMA Internal Medicine found that long-term use of strong anticholinergics was linked to a higher risk of dementia .
